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Targeting Functional Centers of the Ribosome formatIsbn:Hardcover - 9783642169304 i-iv -- Au lectur --

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i-iv -- Au lectur -- Einleitung -- Quellenkritik -- Inhaltsverzeichnis -- Quellenkritik -- I

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Targeting Functional Centers of the Ribosome formatIsbn:Hardcover - 9783642169304 i-iv -- Au lectur --This thesis describes research into the mode of function, inhibition, and evolution of the ribosomal catalytic center, the Peptidyl Transferase Center (PTC) research that has already led to attempts at improving PTC antibiotics. The PhD candidate carried out two parallel studies. One using a combination of X ray crystallography, biochemistry, molecular biology, and theoretical studies to obtain crystal structures of ribosomal particles with

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